Two commonly used meanings:

Point of Presence and Post Office Protocol.
A Point of Presence usually means a city or location where a network can be connected to, often with dial up phone lines. So if an Internet company says they will soon have a POP in Belgrade, it means that they will soon have a local phone number in Belgrade and/or a place where leased lines can connect to their network.

A second meaning, Post Office Protocol refers to a way that e-mail client software such as Eudora gets mail from a mail server. When you obtain an account from an Internet Service Provider (ISP) you almost always get a POP account with it, and it is this POP account that you tell your e-mail software to use to get your mail. Another protocol called IMAP is replacing POP for email.